Dr. Derek Shepherd : I bared my soul to you last night.
Dr. Meredith Grey : It's not enough.
Dr. Derek Shepherd: How can that not be enough?
Dr. Meredith Grey : When you waited two months to tell me, and I had to find out by her showing up, all leggy and fabulous, and telling me herself, you pulled the plug. I'm a sink with an open drain. Anything you say, runs right out. There is no enough. [leaves]
Dr. George O'Malley : She probably could've picked a better metaphor .
Dr. Izzie Stevens : Give her a break. She has a hangover.
(Patrick Dempsey, Ellen Pompeo, and Katherine Heigl in "Enough Is Enough." Grey's Anatomy , 2005)