It is extremely important that figures be prepared with the proper resolution for publication in order to avoid inaccurate presentation of the data. The minimum acceptable resolution for all figures is 300 dpi. Excessive file compression can distort images, so files should be carefully checked after compression. Note that figures that contain both line art (such as graphs) and RGB/grayscale areas (such as photographs) are best prepared as EPS (vector) files with embedded TIFF images for the RGB/grayscale portions. The resolution of those embedded TIFF images should be at least 300 dpi.
Note: Authors are not required to include very long discussions in Methods; succinct and straightforward instructions and troubleshooting of experimental procedures are favored and can be included as notes. Authors should mark in the main text where a note is employed. Relevant notes will be placed close to where they are first mentioned. In this section, authors are expected to include any supplementary explanations that do not fit into the introduction and experimental part. For instance, when a reagent is added at an extremely slow speed or in excess, authors should explain why such a procedure is favored and how it will affect the reaction.